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Our laboratory couples molecular parasitology and structural biology to study the malaria parasite (Plasmodium).


Our research focuses upon:

1. Translational Regulation During Parasite Transmission. 
Our group seeks to understand how specific protein/RNA complexes are used by Plasmodium to produce and maintain a poised state of infectivity to ensure transmission between mosquitoes and mammals.

We focus our efforts on answering mechanistic questions about this process as it occurs in sexual-stage gametocytes and mosquito-transmissible sporozoites.

Surface IFA of sg-spz.tif

2. Parasite Cell Division.

We use Ultrastructure-Expansion Microscopy (U-ExM) and proteomics to investigate how Plasmodium segments itself during cell division.

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