Welcome to the Lindner Laboratory at Penn State in the Department of Biochemistry & Molecular Biology.
Simply stated: our work couples molecular parasitology and structural biology to understand the malaria parasite (Plasmodium spp.), so that we can identify and exploit weaknesses in the parasite’s development and transmission.
Read more about our ongoing Research Interests here.
Scott E. Lindner, Ph.D.
Scott has trained as a molecular virologist, structural biologist, and parasitologist. He is currently an Assistant Professor of Biochemistry and Molecular Biology, and is Co-Director of the Huck Center for Malaria Research at Penn State. He does the Twitter too: @LindnerLab. More info on Scott can be found in his Curriculum Vitae (CV): Lindner SE CV - 20191230.
Trace is the glue that keeps us together. The grease that keeps the wheels turning. The compass to guide us through all logistical waters. You get it. She's vital to our group. Trace is also an exceptional freelance copywriter: besemerwrites.com
Research Tech 4
Allen is our fearless lab manager (except for when it comes to snakes), and resident guru in all things protein expression and purification. Allen trained at Penn State, and mastered his trade in the laboratory of Song Tan here in the BMB department.
Research Tech 1
Mosquito Colony Manager
Mikaela trained at Susquehanna University where she used RNAi to study the EGFR pathway in Drosophila melanogaster. She currently provides us with a near endless supply of Anopheles stephensi mosquitoes for our transmission studies. Mikaela also advances molecular biology projects and sporozoite production efforts. Outside of research she is an avid hiker and the team captain of the MSC Falcons (https://twitter.com/MSCFCFalcons) - a club soccer team for Penn State scientists.
Ph.D. Student (MCIBS)
Mike did his undergraduate studies at the University of Maryland and joined the Lindner Lab in 2014. When Mike isn't dreaming of CRISPR'ing Plasmodium parasites, or digging into the mechanisms of translational repression, he can be found rooting for the Washington Nationals or managing his softball and volleyball teams.
Ph.D. Student (BMMB)
Kelly attended Siena College and conducted undergraduate research on Trypanosoma brucei. Since joining the Lindner Lab in 2015, Kelly has continued to change our views of how Plasmodium organizes its mRNP granules through proteomics and super-resolution microscopy.
Ph.D. Student (BMMB)
Mitchell graduated from the University of Connecticut in Spring 2019, and joined the Lindner Lab in Fall 2019.
James P. McGee
Ph.D. Student (MCIBS)
James graduated from Union College in 2016, and achieved a mastery of Plasmodium falciparum work in the laboratory of Jeff Dvorin at Boston Children's Hospital. Since joining the Lindner Lab in Fall 2019, James has focused on understanding the specialized translational machinery of Plasmodium. When James isn't in lab, you can catch him out on a run, lifting at the gym, or playing defense for the MSC Falcons.
Megan Gragg, Ph.D.
(Joint with Hafenstein Lab)
Megan completed her Ph.D. in Molecular Medicine with Paul Park at Case Western Reserve University in Cleveland, OH, and joined the Lindner and Hafenstein Labs in Fall 2018. Megan focuses on cryo TEM approaches to understand small proteins structurally. When not in lab, Megan can be found reading (fiction) or playing soccer with the MSC Falcons.
B. Joanne Power, Ph.D.
Joanne completed her Ph.D. with Andy Waters at the Wellcome Centre for Integrative Parasitology at the University of Glasgow, where she studied epigenomics and gametocytogenesis of Plasmodium berghei. Since joining the Lindner Lab in 2019, Joanne has focused her work on understanding the release of translational repression programs in transmission stages. Joanne is also a world-renowned Twitter personality (@hanniepower) and curates the Women in Malaria Research website. Find her also on ResearchGate and LinkedIn.
Amy Lee Burns, Ph.D.
Amy completed her Ph.D. with Danny Wilson at the University of Adelaide, where she identified a second mode-of-action of an important antibiotic/anti-malarial drug. Amy will be joining the Lindner Lab in February/March 2020.
Olivia (Liv) Smith
Liv is a senior in the Schreyer Honors College at Penn State, and is majoring in Microbiology. Liv has found an important protein component of the storage granules used for translational repression in Plasmodium. She will graduate in May 2020 and is currently interviewing for Ph.D. programs for Fall 2020.
Lauren is a Senior at Penn State, majoring in Biology and will graduate in May 2020. Her work focuses on an uncharacterized gene that is important for Plasmodium transmission from host to the mosquito. Lauren is currently interviewing for Ph.D. programs for Fall 2020.
Taylor is a Sophomore at Penn State. She will be working on a protein that is important to storage granules found in the transmission stages of Plasmodium starting in January 2020.
Work Study Student
Jena is a Junior at Penn State, majoring in Biomedical Engineering and minoring in Women's Studies. Jena joined the Lindner Lab in Fall 2019 and "keeps the ship afloat" for our molecular biology operations.